Table 2 Association of internet use with new-onset CMDs, CMM, and all-cause death and the mediating role of depressive symptoms

Diabetes

 sHR (95% CI)

0.70 (0.44–1.12)

0.92 (0.81–1.05)

0.87 (0.77–0.99)

0.76 (0.70–0.83)

0.83 (0.74–0.93)

0.061

 Mediation, % (95% CI)

11.7 (4.3–62.5)

4.1 (2.1–7.6)

6.3 (4.4–8.9)

 P values

0.032

0.520

< 0.001

< 0.001

Heart diseases

 sHR (95% CI)

0.92 (0.62–1.34)

1.05 (0.93–1.19)

1.07 (0.95–1.21)

0.86 (0.80–0.92)

0.97 (0.86–1.11)

0.003

 Mediation, % (95% CI)

14.5 (10.3–22.7)

 P values

0.062

0.108

0.098

< 0.001

Stroke

 sHR (95% CI)

0.70 (0.38–1.28)

0.99 (0.75–1.30)

0.84 (0.70–1.01)

0.75 (0.67–0.84)

0.81 (0.71–0.92)

0.264

 Mediation, % (95% CI)

5.6 (3.0-11.3)

8.6 (6.2–12.3)

 P values

0.778

0.338

< 0.001

< 0.001

CMM

 sHR (95% CI)

0.50 (0.27–0.94)

1.12 (0.96–1.30)

0.90 (0.79–1.04)

0.70 (0.62–0.78)

0.83 (0.63–1.09)

< 0.001

 Mediation, % (95% CI)

17.8 (6.8–99.6)

12.0 (5.6–39.2)

10.2 (7.2–14.1)

 P values

0.036

0.076

0.004

< 0.001

All-cause death

 sHR (95% CI)

0.56 (0.27–1.15)

0.91 (0.81–1.02)

0.58 (0.52–0.65)

0.60 (0.56–0.64)

0.67 (0.52–0.86)

< 0.001

 Mediation, % (95% CI)

12.2 (5.5–46.2)

4.0 (2.3–6.7)

5.8 (4.6–7.2)

 P values

0.230

0.010

< 0.001

< 0.001